programme
Monday, March 04, 2024
| Start | End | Session |
| 08:00 11:00 11:15 13:00 13:30 15:40 15:40 16:00 17:00 19:00 19:30 | 11:00 11:15 13:00 13:30 15:40 17:00 16:00 17:00 19:00 21:00 | Opening and Registration Welcoming Address - The Organizing Committee Session 1: Cell-free DNA composition and biology Chairs: Ellen Heitzer & Jochen Geigl DNA methylation-based liquid biopsies Yuval Dor, Israel Mining for hidden cell-free DNA gems Florent Moulière, Netherlands Influence of lifestyle and biological factors on cirDNA Kristina Warton, Australia Unraveling the genetics of cell-free DNA biology using GWAS Jasper Linthorst, Netherlands Elucidating the origins of circulating DNA in diverse cancer types using Nanopore whole-genome sequencing Ben Berman, Israel Sponsored Talk by Illumina Whole exome sequencing of cfDNA in metastatic prostate cancer Tina Moser, Austria Coffee Break & Poster viewing Session 2: Fragmentomics & cfDNA fragments Chairs: Tina Moser & Amit Roshan Expanding the spectrum of cfDNA fragmentomics Dennis Lo, Hong Kong Novel insights on cirDNA fragmentomics and cancer screening Alain Thierry, France Analysis of plasma DNA fragment ends for cancer detection and monitoring Muhammed Murtaza, USA Early detection of cancer using cfDNA fragmentomes Victor Velculescu, USA A novel approach for DNA footprinting using short double-stranded cell-free DNA from plasma Jan Müller, Germany Fragmentomics-based methylation analysis (FRAGMA) of urinary DNA enables detection and localization of cancer in urinary system Qing Zhou, Hong Kong Poster Session 1 Best Poster Candidates Flash Presentations (Topics 1-4 & 10) Coffee break & Poster Viewing Session 3: cfDNA in Physiological and pathological conditions Chairs: Kristina Warton & Yuval Dor Liquid biopsy for infectious disease Iwijn De Vlaminck, USA cfDNA and transplantation Sean Agbor Enoh, USA NIPT update Bernhard Zimmermann, USA Noninvasive prenatal testing using cfDNA and cfRNA: Advances, Challenges and Possibilities Mira N Moufarrej, USA Circulating, cell-free methylated DNA indicates source of allograft injury post-liver transplant Megan E. McNamara, USA Production and origin of circulating DNA and its diagnostic potential in inflammatory diseases Ekaterina Pisareva, France Welcome Reception Speaker Dinner (upon invitation only) |
Tuesday, March 05, 2024
| Start | End | Session |
| 08:30 10:35 11:00 12:45 14:00 15:35 15:35 15:55 16:45 18:30 | 10:35 11:00 12:45 14:00 15:35 16:45 15:55 16:45 18:20 | Session 4: Nucleosomes & open chromatin Michael Speicher Memorial Lecture Chairs: Sarah-Jane Dawson & Tommy Kaplan EPINUC: Single-molecule, multi-modal, analysis of the Epigenetics of Plasma Isolated Nucleosome Efrat Shema, Israel Nucleosome Patterns in ctDNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes Robert Patton, USA TSS profiling to understand response to therapy Dineika Chandrananda, Australia Legacy unveiled: Continuing the journey of nucleosomepositioning in honor of Prof. Michael Speicher Isaac Lazzeri, Austria & Benjamin Gernot Spiegl, Austria High-resolution maps of human nucleosomes from circulating cell-free DNA Roni Schwartz, Israel Universal cell-free DNA Breakpoints in Cancer Patients: Unravelling Chromatin State Nucleosome Dynamics for Advanced Liquid Biopsy Detection Andrew Johnston, Australia Coffee Break & Poster viewing Session 5: Oncology - Early Detection Chairs: Heather Parsons & Alain Thierry Early detection nasopharyngeal cancer Allen Chan, Hong Kong cfDNA in Early Detection of Cancer Nickolas Papadopoulos, USA Detection of pregnancy complications from NIPS profiles Joris Vermeesch, Belgium Complementary analysis of epigenetic and genetic features in plasma und urinary cell-free DNA at first diagnosis of prostate cancer for early detection and risk stratification Anja Lisa Riediger, Germany Circulating Tumor DNA Shedding and Risk of Recurrence in Asymptomatic and Symptomatic Colorectal Cancer Patients: A Comparative Study Nadia Øgaard, Denmark Sponsored Talk by ClearNote Health Epigenomic tools for early cancer detection and therapy response Gulfem Guler, USA Lunch & Poster viewing Session 6: Oncology - MRD Chairs: Samantha Hasenleithner & Isaac Garcia-Murillas Circulating Tumor DNA for Minimal Residual Disease Detection and Risk-Stratified Recurrence Surveillance Claus Andersen, Denmark MRD in Breast cancer Heather Parsons, USA WGS for sensitive ctDNA cancer monitoring Alexandre Pellan Cheng, USA Association between tumor driver mutations and the presence of post-surgical circulating tumor DNA: Insights into tumor biology Miller M. Richters, USA Whole genome sequencing with ppmSeq™ enables efficient and scalable rare variant detection in cell free DNA Itai Rusinek, Israel Poster Session 2 Best Poster Candidates Flash Presentation (Topics 5-9) Coffee Break & Poster Viewing Session 7: Oncology - Monitoring Chairs: Julia Valdemarin Burnier & Claus Lindbjerg Andersen Monitoring low volume disease in cell-free DNA Luis Diaz, USA Treatment-dependent evolution of ctDNA (epi-)genomic features in metastatic prostate cancer Alexander W. Wyatt, Canada Monitoring treatment response in patients with metastatic colorectal cancer Remond Fijneman, Netherlands HPV-ctDNA correlates with disease stage in multiple liquid biopsy analytes in cervical cancer and dysplasia patients Sarah Tadhg Ferrier, Canada Tumor-informed frequent ctDNA monitoring confirms the clinical validity in advanced cancer therapy Satoshi Nishizuka, Japan CNAPS Networking Evening |
Wednesday, March 06, 2024
| Start | End | Session |
| 08:30 10:30 11:00 13:00 14:00 15:35 | 10:30 11:00 13:00 14:00 15:35 16:00 | Session 8: Clinical trials Chairs: Remond J.A. Fijneman & Maximilian Diehn The UK TRACC studies; tissue-free ctDNA-directed de-escalation of adjuvant therapy Naureen Starling, United Kingdom ctDNA analysis in breast cancer trials Isaac Garcia-Murillas, United Kingdom ctDNA guiding adjuvant chemotherapy in localised colorectal cancer: the DYNAMIC trial and beyond Jeanne Tie, USA The Dutch TRIDENT studies; lessons learned and future developments Erik Sistermans, Netherlands Microbial Cell-free DNA Sequencing of Plasma with the Karius Test for Diagnosis of Pneumonia in Immunocompromised Patients Igor Vilfan, USA Potential impact of microbial cfDNA-based metagenomic identification of pathogens on outcome for patients suffering from septic shock Kai Sohn, Germany Coffee Break & Poster viewing Session 9: Bioinformatics approaches for cfDNA analyses Chairs: Dineika Chandrananda & Iwijn de Vlaminck A DNA methylation atlas of normal human cell types Tommy Kaplan, Isreal cfDNA WGS as a community tool Hui Zhao, United Kingdom Novel Bioinformatics/ML approaches for ctDNA analysis: Examples in Triple Negative Breast Cancer Ros Cutts, United Kingdom Improving ctDNA detection by statistical modeling of sequencing errors Jakob Skou Pedersen, Denmark Comprehensive longitudinal tracking of lung cancer evolutionary clonal dynamics during therapy using circulating tumour DNA Alex Frankell, United Kingdom Application of Nanopore sequencing for liquid biopsy analysis in children with cancer Carolin Sauer, United Kingdom Lunch & Poster viewing Session 10: Emerging Frontiers Chairs: Ellen Heitzer & Dennis Lo Accessible and frequent testing using cell-free DNA from dried blood spots Nitzan Rosenfeld, United Kingdom Ultrasensitive ctDNA analysis for detection of minimal residual disease Maximilian Diehn, USA Cell-Free DNA Dynamics of Human Spaceflight (online) Christopher Mason, USA Plasma Cell-free RNA Signatures of Inflammatory Syndromes Conor Loy, USA Dynamic size and association profiles of tumour-derived DNA during pancreatic cancer progression Daniel Hagey, Sweden Announcements of Poster Prize Winner and next CNAPS Closing remark |
Please note that this is only a preliminary programme which is subject to change.
CNAPS2024 Meeting Organizer
Wiener Medizinische Akademie (WMA)
Alser Str. 4, 1090 Wien